The study titled “High Shear Stresses under Exercise Conditions Destroy Circulating Tumor Cells in a Microfluidic System”, conducted by Sagar Regmi, Afu Fu, and Kathy Qian Luo, and published in Nature Scientific Reports, investigates how forces mimicking exercise impact circulating tumor cells (CTCs).

Using engineered breast cancer cells, the researchers observed that lower shear stress levels (15–30 dynes/cm²) had minimal effects on CTCs, whereas higher levels (45–60 dynes/cm²) significantly reduced cell viability. At 60 dynes/cm², nearly all CTCs were destroyed within 9–18 hours.

This research underscores the potential role of high shear stress, similar to that induced by intense exercise, in eliminating CTCs. While exercise holds promise, it is crucial to pair it with a comprehensive health strategy for cancer prevention and overall well-being.

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